We have developed new analysis and visualization methods for extracting scientific information from time series data, images, and 3D (and higher dimensional) surveys of stellar and galaxy positions. These methods have been applied to a number of NASA and other data bases, and applied in a variety of contexts, through programs including the Gamma ray Large Area Space Telescope (GLAST), the Applied Information Systems Research Program, the NASA Engineering and Safety Council (NESC), the Center for Applied Mathematics and Computer Science, the UCLA Institute for Pure and Applied Mathematics, and Puresense, Inc. I will summarize the data analysis techniques and briefly describe programmatic issues.