A brief overview of the Ames New Business Office will be given. Next, the NBO will review examples of non-NASA funding sources that have been obtained by Ames PIs. The process for establishing agreements to carry out work for external agencies will be described along with possible limitations to be aware of. Also, the change from SYS-EYFUS to the new NSPIRES (NASA Solicitation and Proposal Integrated Review and Evaluation System) proposal submission system will be reviewed along with how the center is responding to this change.